Leverage itself is not a risk factor. It only determines how much of your account balance is set aside as initial margin. Leverage is only dangerous when it is abused by taking larger positions, with the corresponding larger risk, than one's account can safely withstand.
It is the position size that is the risk factor, and one should always be aware how much of one's account is at risk should an overall position exposure hit one's stops.
A general rule-of-thumb often used by traders is not to risk more than 1-2% of one's equity at any one time across all open positions unless, for example, some positions already have a locked in profit (i.e. where the stop level is now at break-even or better).
If one has multiple positions then it is wise to also check whether there is any correlation between them in assessing overall exposure.